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CRISPR-Cas Systems 87 My Canadian Leaves - AnCRISPR Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR Cas systems has been identified in at least half of the available prokaryotic genomes. On going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain